Lub Ntiaj Teb yog ib lub ecosystem uas muaj ntau yam sib txawv, thiab peb qhov chaw nyob hauv nws nyob ntawm ntau yam sib txawv. Txij li kev noj qab haus huv ntawm av mus rau qhov zoo ntawm huab cua mus rau tus cwj pwm ntawm cov nroj tsuag thiab cov kab mob me me, kev nkag siab txog peb lub ntiaj teb thiab nws cov neeg nyob hauv yog qhov tseem ceeb rau peb txoj kev ciaj sia. Thaum huab cua hloov pauv tas li, kev kawm txog ib puag ncig thiab nws cov qauv ntawm lub neej yuav tsuas yog qhov tseem ceeb dua.
Thaum Lub Kaum Hli Ntuj xyoo 2023, Advanced Photon Source (APS), ib lub chaw siv hauv Chaw Haujlwm Saib Xyuas Kev Tshawb Fawb ntawm US Department of Energy's (DOE) Argonne National Laboratory, yuav tshaj tawm ib qho kev pab cuam tshiab los nthuav dav kev tshawb fawb thiab kev tshuaj xyuas txog kab mob thiab ib puag ncig ntawm cov chaw soj nstuam loj tshaj plaws hauv ntiaj teb. X-ray teb. Ib lub tuam txhab hu ua eBERlight nyuam qhuav tau txais kev pom zoo los ntawm US Department of Energy's Biological and Environmental Research (BER) program. Lub hom phiaj yog txuas cov kws tshawb fawb ua kev sim ntawm lub luag haujlwm BER nrog APS cov peev txheej kev tshawb fawb X-ray ua tus thawj coj hauv ntiaj teb. Los ntawm kev nthuav dav kev nkag mus rau ntau yam peev xwm ntawm APS, cov neeg xav eBERlight vam tias yuav tshawb pom cov txheej txheem tshawb fawb tshiab thiab nyiam cov pab pawg tshawb fawb tshiab los tshawb nrhiav cov kev xav tshiab ntawm lub ntiaj teb uas peb nyob.
"Qhov no yog ib lub cib fim los tsim ib yam dab tsi tshiab uas tsis tau muaj nyob hauv APS ua ntej," Argonne National Laboratory protein crystallogist Caroline Michalska, uas yog tus thawj coj ua haujlwm ntawm eBERlight tau hais. â�<“我们正在扩大准入范围，以适应更多的生物和环境研究，并且由于该计划是如此新，因此将使用该设施的科学家正在帮助我们开发它。” â <“我们正在扩大准入范围，以适应更多的生物和环境研究，并且由于该计划是如此新。"Peb tab tom nthuav dav kev nkag mus rau hauv kom muaj kev tshawb fawb txog tsiaj txhu thiab ib puag ncig ntau dua, thiab vim tias qhov kev pab cuam no tshiab heev, cov kws tshawb fawb uas yuav siv lub chaw no tab tom pab peb tsim nws."
Txij li thaum nws tau tsim tsa xyoo 1990, APS tau yog tus thawj coj hauv kev tshawb fawb txog "macromolecular crystallography" hauv kev tshawb fawb txog tsiaj txhu. Cov kws tshawb fawb siv cov thev naus laus zis no los kawm ntxiv txog cov kab mob sib kis thiab cov kab mob kom tsim cov tshuaj tiv thaiv kab mob thiab kev kho mob. APS tam sim no lub hom phiaj yog txuas nws txoj kev vam meej mus rau lwm qhov chaw ntawm lub neej thiab kev tshawb fawb ib puag ncig.
Ib qho teeb meem nrog qhov kev nthuav dav no yog tias ntau tus kws tshawb fawb txog tsiaj txhu thiab ib puag ncig tsis paub txog APS lub peev xwm los pab lawv ua kom lawv txoj kev tshawb fawb zoo dua thiab tsis paub txog cov txheej txheem ntawm kev tsim cov duab X-ray ci ntsa iab ntawm ib yam khoom. Ib yam li ntawd, ntau tus kws tshawb fawb tsis paub tias qhov twg ntawm ntau qhov chaw sim APS, hu ua beamlines, yog qhov kev xaiv zoo tshaj plaws rau lawv cov kev sim, vim tias txhua qhov chaw nres tsheb tau ua kom zoo rau ib qho kev tshawb fawb thiab thev naus laus zis tshwj xeeb.
Michalska hais tias qhov no yog qhov uas eBERlight los ua si. Nws piav qhia tias nws yog ib lub ecosystem virtual uas tsim los txuas cov kws tshawb fawb nrog cov thev naus laus zis zoo ntawm txoj kev APS zoo. Cov kws tshawb fawb yuav nthuav qhia cov lus pom zoo rau cov neeg ua haujlwm eBERlight uas yuav pab sib phim qhov kev tsim qauv sim nrog txoj hauv kev kom ua tiav qhov kev tshawb fawb uas tau thov. Nws hais tias qhov sib txawv ntawm APS lub peev xwm txhais tau tias eBERlight tuaj yeem muaj kev cuam tshuam thoob plaws ntau qhov chaw ntawm biology thiab kev tshawb fawb ib puag ncig.
"Peb tab tom saib seb cov kws tshawb fawb BER tab tom kawm dab tsi thiab peb tuaj yeem ua kom tiav qhov kev tshawb fawb ntawd li cas," nws hais. â�<“其中一些研究人员从未使用过APS 等同步加速器. â�<“其中一些研究人员从未使用过APS 等同步加速器."Qee tus kws tshawb fawb no yeej tsis tau siv lub synchrotron zoo li APS."Lawv kawm paub tias muaj cov cuab yeej twg thiab cov lus nug txog kev tshawb fawb twg tuaj yeem teb tau ntawm APS uas tsis tuaj yeem ua rau lwm qhov.
"Qhov no yog ib lub cib fim los tsim ib yam dab tsi tshiab uas tsis tau muaj nyob hauv APS ua ntej. Peb tab tom nthuav dav qhov kev tshawb fawb txog tsiaj txhu thiab ib puag ncig, thiab vim qhov no yog kev tshawb fawb tshiab, cov kws tshawb fawb uas yuav siv lub chaw no tab tom pab peb tsim qhov project." — Caroline Michalska, Argonne National Laboratory
Raws li qhov kev tshawb fawb tshwj xeeb uas eBERlight yuav txhawb nqa, Michalska tau hais tias nws yuav suav nrog txhua yam los ntawm kev tshawb fawb hauv av mus rau kev cog qoob loo, kev tsim huab thiab biofuels. Stefan Vogt, tus lwm thawj coj ntawm APS X-ray Science Division, tau ntxiv lub voj voog dej rau hauv daim ntawv teev npe, sau tseg tias cov ntaub ntawv no yog qhov tseem ceeb rau kev nkag siab zoo dua txog kev hloov pauv huab cua.
"Peb tab tom kawm cov lus nug ntsig txog kev tshawb fawb txog huab cua, thiab peb yuav tsum txuas ntxiv kawm lawv," Vogt hais. â�<“我们需要了解如何应对气候变化对环境的深远影响。” â�<“我们需要了解如何应对气候变化对环境的深远影响。”Peb yuav tsum nkag siab yuav ua li cas los tawm tsam cov teeb meem loj ntawm kev hloov pauv huab cua.
Txawm hais tias eBERlight tau pib ua haujlwm rau lub Kaum Hli Ntuj, APS yuav tseem so ib xyoos ua ib feem ntawm kev txhim kho qhov chaw. Thaum lub sijhawm no, pab neeg yuav ua haujlwm los tshawb nrhiav thiab tsim ib lub tshuab kuaj kab mob thiab ib puag ncig, tsim cov ntaub ntawv khaws cia, thiab ua haujlwm rau qhov kev pab cuam.
Thaum APS rov qab los online dua hauv xyoo 2024, nws cov peev xwm yuav raug nthuav dav heev. Pab neeg eBERlight yuav nkag mus rau hauv cov ntawv cog lus ntev nrog 13 APS channel uas sawv cev rau ntau yam thev naus laus zis. Cov kws tshawb fawb ua haujlwm los ntawm eBERlight kuj tseem yuav muaj kev nkag mus rau Argonne cov peev txheej, xws li Argonne Computing Facility, qhov chaw uas DOE Office of Science Office of Science supercomputers thiab laboratory supercomputers nyob, thiab Center for Advanced Protein Characterization, qhov chaw uas cov protein raug crystallized thiab npaj rau kev tshuaj xyuas.
Thaum qhov kev pab cuam hloov zuj zus, nws yuav siv kev sib txuas nrog lwm lub chaw ua haujlwm DOE Office of Science, xws li Pacific Northwest National Laboratory's Environmental Molecular Sciences Laboratory thiab Joint Genome Institute ntawm Lawrence Berkeley National Laboratory.
"Yuav tsum muaj ib lub zos los tsa ib tug me nyuam, tab sis yuav tsum muaj ib lub zos loj dua los daws teeb meem kev tshawb fawb," tus kws tshawb fawb Argonne Zou Finfrock, ib tug tswv cuab ntawm pab pawg eBERlight hais. â <“Kuv 喜欢eBERlight的多面性，因为它致力于建立一个综合平台，促进跨生物、地球和环境系统的科学探。 â <“Kuv 喜欢eBERlight的多面性，因为它致力于建立一个综合平台，促进跨生物、地球和环境系统的科学探。Kuv nyiam qhov xwm txheej ntawm eBERlight uas muaj ntau yam sib txawv vim nws siv zog los tsim ib lub platform sib koom ua ke uas txhawb nqa kev tshawb fawb txog kev tshawb fawb txog tsiaj txhu, av thiab ecological.Nws zoo li yooj yim xwb, tab sis qhov loj thiab qhov cuam tshuam loj heev.
Lub tswv yim rau eBERlight tau siv sijhawm ntau xyoo los ua, raws li Ken Kemner, tus kws tshawb fawb laus thiab tus thawj coj pab pawg ntawm Argonne National Laboratory. Kemner tau ua haujlwm ntawm APS rau 27 xyoo ntawm lub chaw kuaj mob, feem ntau ntawm nws siv los txuas cov kws tshawb fawb ib puag ncig rau cov peev txheej ntawm lub tsev kawm ntawv. Tam sim no eBERlight yuav txuas ntxiv ua haujlwm no ntawm qhov loj dua, nws hais. Nws tos ntsoov yuav pom cov kev tshawb pom tshiab twg yuav ua los ntawm kev tshawb fawb txog cov pa roj av, cov av noo, thiab kev sib cuam tshuam ntawm cov nroj tsuag thiab cov kab mob me me nrog av thiab cov av av.
Tus yuam sij rau eBERlight txoj kev vam meej, raws li Kemner, yog kev cob qhia cov kws tshawb fawb synchrotron, nrog rau cov kws tshawb fawb txog tsiaj txhu thiab ib puag ncig.
"Koj yuav tsum cob qhia cov kws kho mob radiologist kom nkag siab zoo dua txog cov teeb meem kev tshawb fawb ib puag ncig thiab hloov kho thev naus laus zis los daws cov teeb meem kev tshawb fawb ib puag ncig zoo dua," nws hais. â�<“您还必须教育环境科学家了解光源设施对于解决这些问题有多么出色。 â�<“您还必须教育环境科学家了解光源设施对于解决这些问题有多么出色。Koj kuj yuav tsum qhia cov kws tshawb fawb txog ib puag ncig txog seb cov teeb pom kev zoo li cas los daws cov teeb meem no.Qhov no yog ua tiav txhawm rau txo cov teeb meem kom nyiam lawv.
Laurent Chapon, tus lwm thawj coj ntawm Photon Science Laboratory thiab tus thawj coj ntawm APS, tau hais tias txoj kev npaj tshiab txhais tau tias yuav tsum ua kom muaj kev ywj pheej rau kev nkag mus rau APS thiab nws cov peev xwm.
"Txoj kev npaj no xa ib zaj lus tseem ceeb tias APS yog ib qho chaw tseem ceeb rau lub tebchaws, uas muaj peev xwm tsim cov kev pab cuam uas pab daws cov teeb meem ceev, hauv qhov no yog teeb meem ib puag ncig thiab kab mob," Chapon hais. â�<“eBERlight 将为寻求解决具有现实世界影响的自然科学的科学家提供端到端解到端解刳方。 â�<“eBERlight 将为寻求解决具有现实世界影响的自然科学的科学家提供端到端解到端解刳方。"eBERlight yuav muab kev daws teeb meem dav dav rau cov kws tshawb fawb uas tab tom nrhiav kev daws teeb meem txog kev tshawb fawb txog lub neej uas muaj feem cuam tshuam rau kev siv tiag tiag."
"Kuv vam tias txawm cov kws tshawb fawb yuav ntsib teeb meem loj npaum li cas los xij, APS tuaj yeem pab lawv," nws hais. â�<“这些挑战影响着我们每个人。” â�<“这些挑战影响着我们每个人。”Cov teeb meem no cuam tshuam rau peb txhua tus.
Lub Chaw Argonne Leadership Computing Facility muab kev txawj ntse supercomputing rau cov zej zog kev tshawb fawb thiab kev tsim kho kom txhawb nqa kev tshawb pom thiab kev nkag siab thoob plaws ntau yam kev qhuab qhia. Txhawb nqa los ntawm US Department of Energy's (DOE) Advanced Scientific Computing Research (ASCR) program, ALCF yog ib qho ntawm ob lub chaw suav lej DOE uas mob siab rau kev tshawb fawb qhib.
Lub Chaw Haujlwm Saib Xyuas Zog ntawm Tebchaws Meskas Lub Chaw Haujlwm Saib Xyuas Kev Tshawb Fawb Lub Chaw Haujlwm Saib Xyuas Kev Tshawb Fawb (APS) ntawm Argonne National Laboratory yog ib qho ntawm cov chaw tsim hluav taws xob X-ray zoo tshaj plaws hauv ntiaj teb. APS muab cov duab X-ray ci ntsa iab rau ntau pawg neeg tshawb fawb hauv kev tshawb fawb txog cov ntaub ntawv, chemistry, condensed matter physics, lub neej thiab kev tshawb fawb ib puag ncig, thiab kev tshawb fawb siv. Cov duab X-ray no zoo tagnrho rau kev kawm cov ntaub ntawv thiab cov qauv ntawm lub cev; kev faib tawm ntawm cov ntsiab lus; cov xwm txheej tshuaj lom neeg, hlau nplaum thiab hluav taws xob; nrog rau ntau yam kev tsim kho tshuab tseem ceeb, los ntawm roj teeb mus rau cov taub hau txhaj tshuaj, uas yog qhov tseem ceeb rau peb lub tebchaws kev lag luam, kev siv tshuab thiab kev lag luam. thiab Lub hauv paus ntawm kev noj qab haus huv ntawm cov khoom siv. Txhua xyoo, ntau dua 5,000 tus kws tshawb fawb siv APS los tsim ntau dua 2,000 phau ntawv tshaj tawm, piav qhia txog cov kev tshawb pom tseem ceeb thiab daws cov qauv protein tseem ceeb dua li lwm tus neeg siv cov chaw tshawb fawb X-ray. Cov thev naus laus zis tshiab ntawm APS cov kws tshawb fawb thiab cov engineers yog lub hauv paus ntawm kev tsim cov accelerators thiab cov chaw teeb pom kev zoo. Cov no suav nrog cov khoom siv nkag uas tsim cov duab X-ray ci ntsa iab uas cov kws tshawb fawb nyiam, cov iav uas tsom cov duab X-ray mus rau ob peb nanometers, cov cuab yeej uas ua kom muaj kev sib cuam tshuam ntawm cov duab X-ray nrog cov qauv uas tab tom kawm, thiab cov khoom siv uas sau thiab sib sau ua ke cov software X-ray. Tswj cov ntaub ntawv loj heev los ntawm kev tshawb fawb APS.
Daim kev tshawb fawb no siv cov peev txheej los ntawm Advanced Photon Source, uas yog ib qho chaw siv rau cov neeg siv DOE Office of Science uas tswj hwm los ntawm DOE Office of Science's Argonne National Laboratory raws li Daim Ntawv Cog Lus No. DE-AC02-06CH11357.
Argonne National Laboratory tau cog lus tias yuav daws cov teeb meem kev tshawb fawb thiab thev naus laus zis hauv tebchaws. Argonne National Laboratory, lub chaw kuaj mob hauv tebchaws thawj zaug hauv Tebchaws Meskas, ua cov kev tshawb fawb yooj yim thiab siv tau zoo tshaj plaws hauv txhua qhov kev qhuab qhia txog kev tshawb fawb. Cov kws tshawb fawb ntawm Argonne National Laboratory ua haujlwm nrog cov kws tshawb fawb los ntawm ntau pua lub tuam txhab, tsev kawm qib siab, thiab cov koom haum hauv tsoomfwv, xeev thiab nroog los pab lawv daws cov teeb meem tshwj xeeb, txhawb kev coj noj coj ua ntawm kev tshawb fawb hauv Tebchaws Meskas, thiab tsim kom muaj lub neej yav tom ntej zoo dua rau lub tebchaws. Argonne muaj cov neeg ua haujlwm ntau dua 60 haiv neeg thiab tswj hwm los ntawm Argonne LLC hauv Chicago, ib feem ntawm US Department of Energy's Office of Science.
Lub Chaw Haujlwm Saib Xyuas Zog ntawm Tebchaws Meskas yog lub koom haum pab nyiaj loj tshaj plaws rau kev tshawb fawb txog lub cev hauv Tebchaws Meskas thiab tab tom ua haujlwm los daws qee qhov teeb meem nyuaj tshaj plaws ntawm peb lub sijhawm. Yog xav paub ntxiv, mus saib https://energygy.gov/science.
Lub sijhawm tshaj tawm: Kaum Ib Hlis-06-2023